Literature summary for 3.4.24.85 extracted from

Iwata, Y.; Ashida, M.; Hasegawa, C.; Tabara, K.; Mishiba, K.I.; Koizumi, N.
Activation of the Arabidopsis membrane-bound transcription factor bZIP28 is mediated by site-2 protease, but not site-1 protease (2017), Plant J., 91, 408-415 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
membrane-bound inactive transcription factor fragment bZIP28X1 + H2O	Arabidopsis thaliana	transcription factor bZIP28 is cleaved within the transmembrane domain, and the N-terminal portion containing the bZIP domain is released from the membrane to translocate into the nucleus, where it activates the ER stress-responsive genes	?	-	?
membrane-bound inactive transcription factor fragment bZIP28X2 + H2O	Arabidopsis thaliana	transcription factor bZIP28 is cleaved within the transmembrane domain, and the N-terminal portion containing the bZIP domain is released from the membrane to translocate into the nucleus, where it activates the ER stress-responsive genes	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	ecotype Col-0	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
membrane-bound inactive transcription factor fragment bZIP28X1 + H2O	transcription factor bZIP28 is cleaved within the transmembrane domain, and the N-terminal portion containing the bZIP domain is released from the membrane to translocate into the nucleus, where it activates the ER stress-responsive genes	Arabidopsis thaliana	?	-	?
membrane-bound inactive transcription factor fragment bZIP28X2 + H2O	transcription factor bZIP28 is cleaved within the transmembrane domain, and the N-terminal portion containing the bZIP domain is released from the membrane to translocate into the nucleus, where it activates the ER stress-responsive genes	Arabidopsis thaliana	?	-	?

Synonyms

Synonyms	Comment	Organism
S2P	-	Arabidopsis thaliana
site-2 protease	-	Arabidopsis thaliana

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Release 2023.1 (January 2023)